Physical force alone spurs gene expression, study reveals

“Living cells in the human body experience forces of various frequencies (for example breathing, heartbeats, walking, running, jumping and singing), typically ranging from 0.2 hertz to hundreds of hertz,” the researchers wrote. At the highest frequencies, cells became stiffer and the enzymes that guide gene transcription could not bind to the DNA, the team found.Cells’ immediate responsiveness to force makes sense from an evolutionary perspective, Wang said.”Cells must be able to respond quickly to things in their environment so they can survive,” he said.

Source: Physical force alone spurs gene expression, study reveals